A day 1 hCG can differentiate non-viable intrauterine pregnancy and ectopic pregnancy following endometrial curettage

Main Article Content

Ozgur Kara
Gulenay Gencosmanoglu Turkmen
Halil Korkut Daglar
Cem Yasar Sanhal
Bergen Laleli Koc
Aykan Yucel
Dilek Sahin

Abstract

Aim: The aim of the present study was to determine a cutoff level for a decrease in human chorionic gonadotropin (hCG) on postoperative day 1 to confirm intrauterine pregnancy (IUP) in patients who have undergone dilatation and curettage (D/C) with a presumptive diagnosis of nonviable pregnancy of unknown location (PUL). Material and Methods: This retrospective case–control study included patients who underwent D/C with a presumptive diagnosis of failing PUL between January 2010 and June 2015. Patients with failing PUL or confirmed to have an IUP were placed in Group 1 (n=164) and patients subsequently diagnosed with ectopic pregnancy were placed in Group 2 (n=19).In all patients, serum hCG levels were obtained on the day of D/C and on the following day.Results: The decline in serum hCG percentage on day 1 after D/C was 54.2% in patients with failing PUL/abortion and 14.3% in patients with ectopic pregnancy (p0.001). A decrease in hCG of more than 35% was the most sensitive marker, with sensitivity, specificity, and positive and negative predictive values of 90%, 89%, 99%, and 50%, respectively.Conclusion: Determining post curettage day 1 hCG might aid clinicians in confirming failing IUP and in ruling out an ectopic pregnancy at an earlier date.

Downloads

Download data is not yet available.

Article Details

How to Cite
Kara, O., Gencosmanoglu Turkmen, G., Korkut Daglar, H., Yasar Sanhal, C., Laleli Koc, B., Yucel, A., & Sahin, D. (2021). A day 1 hCG can differentiate non-viable intrauterine pregnancy and ectopic pregnancy following endometrial curettage . Annals of Medical Research, 27(5), 1422–1427. Retrieved from http://annalsmedres.org/index.php/aomr/article/view/765
Section
Original Articles