Assessment of vitamin D levels in patients with sudden sensorineural hearing loss

Main Article Content

Elif Sari
Taskin Tokat
Aynur Aliyeva
Mehmet Karadag
Fatma Eren
Tolgahan Catli
Levent Olgun

Abstract

Aim: Vitamin D is important in antiproliferative, immunomodulatory, prodifferentiative effects, metabolic functions, and neuromuscular activity. We try to evaluate the relation between vitamin D deficiency and Idiopathic Sudden  Sensorineural Hearing Loss (ISSHL) and its impact on response to treatment.


Materials and Methods: This study was performed prospectively in 2 groups, 55 participants with SSHL and 55 with normal hearing without middle ear pathology. All patient information such as age, gender, lipid values, coagulation parameters, audiometry results, and vitamin D level was recorded at baseline. Patients with SSHL received steroid therapy at a decreasing dose of 1 mg/kg/day, and their response to treatment had evaluated according to posttreatment audiometry tests.


Results: Vitamin D level in the SSHL group with a mean of 17.27±15.73 ng/ml was significantly less than the control group (31.31±27.21 ng/ml; p-value =0.001). The mean pure-tone audiometry (PTA) before treatment was 62.74±23.66 dB HL (range 28-117 dB) and 45.24±23.47 dB HL after treatment (range 6-101 dB HL). The patient group with less vitamin D values was statistically significant than the group with normal vitamin D values in terms of mean PTA before and after treatment (respectively: p=0.010; p=0.002). Pretreatment and posttreatment hearing levels were statistically higher in the group with normal vitamin D. Vitamin D values below 22.16 were a risk factor for sudden hearing loss (p=0.001).


Conclusion: In our study, participials with SSHL found a higher vitamin D deficiency level. The role of pathophysiological mechanisms underlying SSHL remains uncertain; vitamin D affecting these mechanisms seems to be an important prognostic factor.

Downloads

Download data is not yet available.

Article Details

How to Cite
Sari, E., Tokat, T., Aliyeva, A., Karadag, M., Eren, F., Catli, T., & Olgun, L. (2023). Assessment of vitamin D levels in patients with sudden sensorineural hearing loss. Annals of Medical Research, 30(5), 538–544. Retrieved from http://annalsmedres.org/index.php/aomr/article/view/4422
Section
Original Articles