The role of preoperative complete blood count indices in the distinction of papillary thyroid cancer from nodular goiter

Authors

  • Ahmet Karayigit University of Health Sciences, Adana City Training and Research Hospital, Department of Surgical Oncology, Adana, Türkiye
  • Umit Ozdemir University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Department of Gastroenterology Surgery, Ankara, Türkiye
  • Dursun Burak Ozdemir University of Health Sciences, Samsun Education and Research Hospital, Department of Surgical Oncology, Samsun, Türkiye
  • Hayrettin Dizen Acibadem Eskisehir Hospital, Department of General Surgery, Eskisehir, Türkiye
  • Bulent Unal Istanbul Aydin University, Faculty of Medicine, Medical Park Florya Hospital, Department of Organ Transplantation, Istanbul, Türkiye

Keywords:

Oncology, Nodular goiter, Papillary thyroid cancer, Neutrophil-to-lymphocyte ratio, Platelet-to-lymphocyte ratio

Abstract

Aim: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios (respectively, NLR and PLR) have been associated with poor prognosis in various cancers. This study was conducted to investigate PLR and NLR in patients with papillary thyroid cancer (PTC) and nodular goiter (NG).

Materials and Methods: Patients who had undergone thyroidectomy at our center were reviewed and the demographic, clinical and histopathological characteristics of patients with PTC or NG were recorded. Hemogram (complete blood count) results were used to calculate NLR and PLR.

Results: The groups were similar with respect to age, gender and thyroiditis characteristics. The NG group was found to have significantly larger gland size compared to the PTC group. NLR and PLR values were similar in the two groups (p=0.556 and p= 0.841 respectively).

Conclusion: PLR and NLR appear to be exceedingly similar in PTC and NG, and therefore, they cannot be used to distinguish between PTC and NG. However, it may be valuable to conduct future studies that take into account lesion size when comparing these parameters in thyroid nodules.

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Published

2022-11-23

Issue

Vol. 29 No. 11 (2022): November

Section

Original Articles

License

Copyright (c) 2022 Annals of Medical Research

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

CC Attribution-NonCommercial-NoDerivatives 4.0

How to Cite

1.
The role of preoperative complete blood count indices in the distinction of papillary thyroid cancer from nodular goiter. Ann Med Res [Internet]. 2022 Nov. 23 [cited 2025 Feb. 23];29(11):1200-4. Available from: http://annalsmedres.org/index.php/aomr/article/view/4329