The investigation of ischemia modified albumin, sialic acid and malondialdehyde levels in cupping blood of interscapular area in women with headache, backache and low back pain

Abstract

Aim: Ischemia modified albumin (IMA), sialic acid and malondialdehyde (MDA) are the most frequently used biomarker of oxidative stress in many health problems. In this study, it was aimed to investigate the relationship between IMA, sialic acid and MDA levels and visual analogue scale (VAS) pain scores in the cupping blood of the interscapular region in women with headache, low back pain, and backache.

Materials and Methods: This study was performed on 96 women between the ages of 18-55. Participants were divided into three groups according to complaints of backache (30 women, group 1), low back pain (31 women, group 2) and headache (35 women, group 3) . IMA, sialic acid and MDA levels were measured spectrophotometrically in the cupping blood of the interscapular region.

Results: There was no significant difference between IMA, sialic acid and MDA levels in the cupping blood of the interscapular region of groups. There was a statistically significant positive correlation between MDA levels of group 1, group 2 and group 3 and VAS values (p <0.01). In addition, there was a statistically significant positive correlation between sialic acid levels and VAS values of group 1 and group 3 (p <0.01). In addition, statistically significant positive correlation was found between IMA levels and VAS values of group 3 (p <0.01).

Conclusion: Our study was the first study in the literature investigating the MDA, IMA and sialic acid levels in the cupping blood in the differential diagnosis of different region pain types. The levels of these parameters were not found to be different in distinguishing different region etiologies of pain in the obtained findings. However, according to our VAS scores, there was a decrease the pain of the patients after cupping therapy and the relationship between these values and oxidative parameters was also determined.