Differences in the clinical course, laboratory and radiological findings of COVID-19 infection between male, female and pregnant patients in demographically homogeneous groups

Authors

  • Hilal Gulsum Turan Ozsoy Bursa City Hospital, Department of Radiology, Bursa, Türkiye
  • Serhat Unal Bursa City Hospital, Department of Obstetrics and Gynecology, Bursa, Türkiye
  • Isa Kilic Bursa City Hospital, Department of Radiology, Bursa, Türkiye
  • Behiye Oral Bursa City Hospital, Department of Anesthesiology and Reanimation, Intensive Care Unit, Bursa, Türkiye

Keywords:

COVID 19, Pregnancy, Gender

Abstract

Aim: This study examines for any differences in the clinical course, laboratory and radiological findings of COVID-19 infection between male, female and pregnant patients in similar age groups.

Materials and Methods: This  retrospective study involved a review of the data of patients treated between March 2020 and May 2021, included a total of 528 cases (193 pregnant females, 170 non-pregnant females and 165 males) aged 18–40 years with RT-PCR-confirmed COVID-19.

Results: A comparison of the three demographically homogeneous groups revealed more common symptomatic infection at admission in the male patient group than in the other two patient groups (p<0.001), as well as a longer hospital stay (p<0.001) and higher incidences of moderate and severe pneumonia (p<0.001) based on radiological findings. In contrast, no significant difference was noted in the intensive care unit admission and mortality rates of the three groups.

Conclusion: The results of our study reveal that females have some degree of protection against severe presentations of COVID-19 infection when compared to men. The heterogeneity of immunocompetence and immune response can help to understand the different COVID-19 responses of males and females, and can be used as a guide for disease prognosis and gender-specific treatments.

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Published

2023-01-21

Issue

Section

Original Articles

How to Cite

1.
Differences in the clinical course, laboratory and radiological findings of COVID-19 infection between male, female and pregnant patients in demographically homogeneous groups. Ann Med Res [Internet]. 2023 Jan. 21 [cited 2025 Apr. 2];30(1):70-5. Available from: http://annalsmedres.org/index.php/aomr/article/view/4196