The importance of inflammation markers in the diagnosis of COVID-19 in children inflammation markers in the diagnosis of COVID-19 in children

Authors

  • Meyri Arzu Yoldas Bolu Abant Izzet Baysal University, Faculty of Medicine, Department of Pediatrics, Bolu, Türkiye
  • Gokce Kaya Dincel Ankara City Hospital, Department of Pediatrics, Ankara, Türkiye
  • Halil Ibrahim Atasoy Bolu Abant Izzet Baysal University, Faculty of Medicine, Department of Pediatrics, Bolu, Türkiye
  • Sinan Tas Bolu Abant Izzet Baysal University, Faculty of Medicine, Department of Pediatrics, Bolu, Türkiye
  • Mustafa Dilek Bolu Abant Izzet Baysal University, Faculty of Medicine, Department of Pediatrics, Division of Neonatology, Bolu, Türkiye

Keywords:

Children, COVID-19, NLR, PLR, Polymerase chain reaction

Abstract

Aim: To predict the presence of COVID-19 by readily available hematological and biochemical tests.

Materials and Methods: A total of 58 children with signs indicative of COVID-19 (28 PCR positive for SARS-CoV2 and 30 negative) were included in this retrospective study. Clinical and laboratory parameters were compared between the groups.

Results: White blood cell counts, RDW, MPV, NLR, PLR, LDH and CRP values were found to be higher in pediatric patients with positive PCR tests than children with negative PCR tests (p<0.05). There was a significantly positive correlation between CRP and NLR (r=.566, p<0.001), CRP and PLR (r=.462, p<0.001).

Conclusion: CRP, NLR and PLR, which are frequently used as inflammation markers, can help predict PCR positivity for SARS-CoV2. These easy-to-use,  tests can guide diagnosis in countries where access to PCR tests is limited.

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Published

2022-07-25

Issue

Section

Original Articles

How to Cite

1.
The importance of inflammation markers in the diagnosis of COVID-19 in children inflammation markers in the diagnosis of COVID-19 in children. Ann Med Res [Internet]. 2022 Jul. 25 [cited 2025 Feb. 23];29(7):673-7. Available from: http://annalsmedres.org/index.php/aomr/article/view/4195