Serum amyloid-a may be an early marker in diagnosis of preterm premature rupture of membrane and chorioamnionitis

Authors

  • Hatice Kayabas
  • Fatma Devran Bildircin
  • Bahattin Avci
  • Pervin Karli
  • Ayse Zehra Ozdemir
  • Tayfun Alper

Keywords:

Premature rupture of membrane, chorioamnionitis, serum Amiloid A

Abstract

Aim: To determine the efficiency of serum amyloid-A (SAA) in predicting preterm premature rupture of membrane (PPROM) and chorioamnionitis in risky cases. Study Design: The study consists of 20 women 26-37 weeks of pregnancy who had PPROM and 20 pregnant women without water breaks. Levels of SAA were determined in maternal venous and umbilical cord blood. Results: SAA values in cord blood and venous blood of mothers with PPROM were higher than in the control group (p0,05). SAA values in the patients with clinical chorioamnionitis (n=9) were significantly higher (p0,05) than both PPROM patients without chorioamnionitis (n=11) and the control group (n=20). Conclusion: In women at risk for PPROM in whom diagnosis cannot be established, blood SSA levels can be used as a marker. Increased SAA values in pregnant women with PPROM who were conservatively treated were considered a marker for chorioamnionitis.

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Published

2021-05-25

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Original Articles

How to Cite

1.
Serum amyloid-a may be an early marker in diagnosis of preterm premature rupture of membrane and chorioamnionitis . Ann Med Res [Internet]. 2021 May 25 [cited 2025 Apr. 2];26(12):2802-6. Available from: http://annalsmedres.org/index.php/aomr/article/view/1911