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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

    In publication or citation search, the name similarities of the authors, typographical errors and institutional changes can cause confusion. To prevent this, researchers need to obtain a descriptive ID. ORCID (Open Researcher and Contributor ID) is a researcher-specific international URI with a 16-digit number. You can register for free for individual ORCID at http://orcid.org. Please indicate the ORCID number of all authors when submitting your article.

  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is It is published monthly.

Editor-in-Chief
Cuneyt Kayaalp

 

Monocyte / high-density lipoprotein ratio and neutrophil-to-lymphocyte ratio in age-related macular degeneration (p. 1880-4)

Monocyte / high-density lipoprotein ratio and neutrophil-to-lymphocyte ratio in age-related macular degeneration (p. 1880-4)

Bekir Kucuk, Ender Sirakaya, Zeynep Duru, Necati Duru
Kayseri City Hospital, Department of Ophthalmology, Kayseri, Turkey

Abstract

Aim To evaluate the monocyte/high-density lipoprotein (HDL) ratio (MHR) and neutrophil-to-lymphocyte ratio (NLR) as biomarkers of systemic inflammation in age-related macular degeneration (AMD).
Materials and Methods: HDL, hematological profiles, erythrocyte sedimentation rates, C-reactive protein, MHRs, and NLRs were evaluated in 30 patients with neovascular AMD (Group 1), 30 with non-neovascular AMD (Group 2), and 30 controls (Group 3).
Results: MHRs and NLRs were significantly higher in Group 1 than in Group 3 (p = 0.002 and p 0.001, respectively) and were independent predictors of neovascular AMD in multivariate analysis (odds ratio = 1.231 and 3.332; 95% confidence interval = 1.035–1.466 and 1.385–8.019; p = 0.019 and 0.007, respectively). The areas under the receiver operating characteristics curve for MHR and NLR were 0.669 and 0.769. The sensitivity and specificity of MHRs and NLRs in predicting neovascular AMD were 47% and 97% versus 63% and 80%, respectively.
Conclusions: By reflecting the balance of pro- and anti-inflammatory responses, the MHR can reliably indicate systemic inflammation in AMD.
Keywords: Age-related macular degeneration; monocyte-to-high-density lipoprotein ratio; neutrophil-to-lymphocyte ratio; systemic inflammation; neovascular AMD.

 

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doi: 10.5455/annalsmedres.2019.06.354

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Inonu University Faculty of Medicine

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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