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  • Annals of Medical Research

    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil


Annals of Medical Research


Magnetic resonance imaging with dynamic contrast enhancement in perianal fistula staging (p.657-62)

Magnetic resonance imaging with dynamic contrast enhancement in perianal fistula staging (p.657-62)

Safiye Sanem Dereli Bulut, Zakir Sakci
Department of Radiology, TC.Health Sciences University, Umraniye Research and Training Hospital, Istanbul, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.


Aim: To investigate whether dynamic contrast enhanced perfusion T1-weighted (DCE T1-W) three-dimensional volume interpolated breath-hold examination (3-D vibe) contributes to perianal fistula staging.
Materials and Methods: A total of 110 patients who underwent pelvic magnetic resonance imaging (MRI) (1,5 tesla, Siemens, Avanto) with the preliminary diagnosis of perianal fistula were included in our retrospective study. In our perianal fistula MRI protocol, DCE T1-W 3D vibe sequence was in axial plane with fat-saturation and in five phases (precontrast phase and then in the 45th, 60th, 180th and 240th seconds after intravenous contrast administration). Perianal fistula staging was performed according to T2-weighted sequence findings (acute, subacute, chronic) and by clinical history. Semi-quantitative measurements of the perianal fistula were made with the ROIs placed on the perianal fistula and left femoral artery. Then measurements were made as follows: Type of contrast curve obtained, staining peak time and slope angle of the curve. All measurements were performed independently by two radiologists at different times. Interobserver agreement was also evaluated (Cohen’s kappa).
Results: The phases of reaching the peak time (TTP) of contrast increases as the perianal fistula stage increases (mean phases of TTP values were 2.2 th± 1.2 in acute phase fistulas, 2.8 th ± 1.2 in subacute perianal fistulas; 4.4 th ± 1 in chronic fistulas). The angle of inclination decreased as the stage of the perianal fistula increased (42.2 ± 13.2 degrees; 27 ± 11.3 degrees and 9.6 ± 2.3 degrees, respectively).
Conclusion: Diagnosis of perianal fistula with physical examination can be confusing. Sometimes there can be fistulas with different stages in the same patient. Therefore, the use of IV contrast-enhanced pelvic examination with dynamic technique may provide information about the perianal fistula stage.

Keywords: Dynamic contrast enhanced imaging; fibrosis; magnetic resonance imaging; perianal fistula

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doi: 10.5455/annalsmedres.2020.06.610     


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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.



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