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  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil

Editor-in-Chief

Annals of Medical Research

 

Non-cystic fibrosis bronchiectasis: Etiologic approach and effects of long-term azithromycin in children (p.685-8)

Non-cystic fibrosis bronchiectasis: Etiologic approach and effects of long-term azithromycin in children (p.685-8)

Ayse Ayzit Kilinc, Haluk Cokugras
Department of Pediatric Pulmonology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: Non-cystic fibrosis bronchiectasis (NCFB) is a chronic pulmonary problem that includes a group of heterogeneous diseases. Macrolide antibiotics are increasingly prescribed for patients with NCFB, but there are very few studies on their use in children. This study aimed to search the clinical features of children with NCFB and the effect of long-term use of azithromycin on the frequency of aggravation, microbiological reproduction, and pulmonary function tests.
Materials and Methods: A total of 79 cases diagnosed with NCFB were recorded. Clinical, laboratory, and radiological evaluations were also recorded. Exacerbation frequency, sputum cultures, and pulmonary function tests of 27 children who received azithromycin before and during prophylaxis were also analyzed.
Results: The median age of children was 7.6 years old (1 to 16 years), when the children were diagnosed with NCFB. Bronchiectasis etiology was detected in 62 patients. Primary ciliary dyskinesia (PCD) was the most common cause of bronchiectasis, which 24 (30%) children were diagnosed with PCD. Azithromycin treatment was given to 27 bronchiectasis patients for six months. A statistically significant decrease was detected in pulmonary aggravation frequency and sputum microbiology during azithromycin treatment (p 0.05)
Conclusion: The use of azithromycin in children with NCFB improves aggravation frequency but has no significant effect on the pulmonary function test.

Keywords: Azithromycin; non-cystic fibrosis bronchiectasis; primary ciliary dyskinesia; pulmonary exacerbation

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doi: 10.5455/annalsmedres.2020.03.278     

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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