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  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil

Editor-in-Chief

Annals of Medical Research

 

Comparison of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in patients diagnosed with trigeminal neuralgia and healthy controls (p.704-8)

Comparison of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in patients diagnosed with trigeminal neuralgia and healthy controls (p.704-8)

Erman Altunisik, Ali Zeynel Abidin Tak
Department of Neurology, Adiyaman University Education and Research Hospital, Adiyaman, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: Trigeminal neuralgia (TN) is a common cranial nerve disease, but its pathogenesis has not yet been fully elucidated. The neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) have been investigated in recent years as markers of systemic inflammation, and their determination presents as a lower-cost, more practical, and simpler method compared to other inflammation markers. This study aimed to evaluate the possible role of systemic inflammation in TN etiopathogenesis based on NLR and PLR values.
Materials and Methods: The study included 55 male and female patients aged 18 to 60 years, who were diagnosed with TN at the Neurology Clinic of our university according to the criteria of Headache Classification Committee of the International Headache Society 2018 (Cephalalgia2018), and 48 healthy controls. Demographic and clinical variables, such as age and gender were retrospectively obtained from medical records.
Results: In terms of sociodemographic data, both groups had similar characteristics. The NLR values were 1.84±0.81 for the patient group and 1.92±0.79 for the control group. There was no statistically significant difference in NLR between the two groups (p = 0.447). The PLR values were 101.91±30.24 and 97.84±30.24 for the patient and control groups, respectively, indicating no statistically significant difference (p = 0.439).
Conclusions: The role of systemic inflammation in TN pathophysiology remains controversial. It is considered that an inflammatory process may occur in the pathophysiology of TN, but this is characterized by local neurogenic inflammation rather than the effect of a systemic inflammatory response.

Keywords: Cranial nerve; headache; inflammation; neutrophil-lymphocyte ratio; platelet-lymphocyte ratio; trigeminal neuralgia

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doi: 10.5455/annalsmedres.2020.05.437     

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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