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  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil

Editor-in-Chief

Annals of Medical Research

 

Detecting the presence of inflammation in fibromyalgia syndrome with neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and mean platelet volume (p.722-5)

Detecting the presence of inflammation in fibromyalgia syndrome with neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and mean platelet volume (p.722-5)

Murat Guntel1, Alper Uysal2
1Department of Neurology, Tayfur Ata Sokmen Faculty of Medicine, Hatay Mustafa Kemal University, Hatay Turkey
2Clinic of Physical Medicine and Rehabilitation, Hatay State Hospital, Hatay, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: Our purpose was to determine the presence of inflammation in Fibromyalgia Syndrome (FMS), whether the parameters of neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) and mean platelet volume (MPV) can be used as inflammation markers.
Materials and Methods: FMS patients who applied to Hatay State Hospital Physical Medicine and Rehabilitation Clinic in the last two years were analyzed retrospectively from the patient records. 92 participants were enrolled in the study, 43 of them were FMS patients, and 49 were healthy control group. Hemogram, glucose levels, hepatic panel and renal function tests, thyroid and parathyroid function testing, vitamin B12 and 25-hydroxyvitamin D, serum iron panel, folate, lipid panel, erythrocyte sedimentation rate (ESR), C-reactive protein, RF, Bucella agglutination test results were evaluated. Thus, patients with diseases that could affect NLR, PLR, and MPV were not enrolled in the study.
Results: No significant difference between the groups in terms of gender distribution was found (p = 0.999). No significant difference between the groups in terms of age was found (p=0.327). When the groups were compared in terms of MPV, the values were found to be lower in the FMS group. Statistically significant difference was not found in both groups in terms of NLR, PLR, White blood count (WBC) and Platelet (PLT) levels (p=0.106; p=0.710; p=0.271; p=0.141, respectively).
Conclusion: A significant difference was not found in both groups in terms of NLR and PLR, which were thought to be inflammation markers. The statistically significant higher values of mean ESR values in the FMS group indicate that inflammation may be present in the pathogenesis of FMS, but NLR and PLR cannot be used as indicators of inflammation, so correlating these rates with the severity of symptoms would be meaningless.

Keywords: Fibromyalgia syndrome; inflammation; mean platelet volume; neutrophil lymphocyte ratio; platelet lymphocyte ratio

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doi: 10.5455/annalsmedres.2020.08.892    

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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