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  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil

Editor-in-Chief

Annals of Medical Research

 

The role of Diffusion-weighted magnetic resonance imaging and apparent diffusion coefficient (ADC) values in the evaluation of solid breast lesions (p.755-8)

The role of Diffusion-weighted magnetic resonance imaging and apparent diffusion coefficient (ADC) values in the evaluation of solid breast lesions (p.755-8)

Sukru Oguz1, Alper Ozel2
1Department of Radiology, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey
2Department of Radiology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: To investigate the role of Diffusion-weighted magnetic resonance imaging and apparent diffusion coefficient (ADC) values in the differential diagnosis of solid lesions of the breast.
Materials and Methods: Diffusion-weighted images and ADC values from 36 women with 37 solid lesions definitely diagnosed through breast biopsy and post-surgical histopathology were evaluated retrospectively. ADC values obtained from malignant and benign solid lesions of the breast were compared using the t-test. The optimum threshold value for use in differentiating benign and malignant lesions was determined using ROC analysis, and sensitivity and specificity values were calculated.
Results: Histological analysis identified 23 lesions and 14 benign lesions. Mean age (49 ± 7.8 years) was higher in the group with malignant breast lesions than in the group with benign breast lesions (37.3 ± 8.2) (p 0.05). The mean ADC value (1.1 ± 0.2 × 10-3 mm2/s) in the patients with malignant breast lesions was significantly lower than in the group with benign breast lesions (1.49 ± 0.18 × 10-3 mm2/s) (p 0.05). When the threshold value to be used in the ROC curve was applied the differentiation of benign and malignant solid lesions, the sensitivity was 78.3% and specificity was 100%.
Conclusions: Diffusion-weighted MRI and ADC values have the potential to contribute to the diagnosis of solid lesions in the breast at conventional MR examination by differentiating between benign and malignant tumors.

Keywords: ADC value; breast lesions; diffusion-weighted MRI

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doi: 10.5455/annalsmedres.2020.03.281    

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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