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  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil

Editor-in-Chief

Annals of Medical Research

 

The efficacy of divalent iron preparations with and without zinc in the treatment of iron deficiency anemia (p.511-5)

The efficacy of divalent iron preparations with and without zinc in the treatment of iron deficiency anemia (p.511-5)

Zeynep Canan Ozdemir1, Yeter Duzenli Kar1, Yasemin Ersozlu2, Hatice Burcu Caglar2, Ozcan Bor1
1Department of Pediatrics, Division of Hematology and Oncology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey
2Department of Pediatrics, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: Iron deficiency anemia (IDA) is the most frequently detected cause of anemia in Turkey and worldwide. In this study, we investigated the efficacy of the iron preparations of ferrous sulfate (group FeS, Fe2+) and ferrous fumarate combined with Zn (group Fe2+-Zn) in the treatment of IDA.
Materials and Methods: Seventy children receiving FeS and 24 children receiving Fe2+-Zn due to IDA between June 2018 and January 2019 were included in the study. The Hb, MCV, MCH, RBC, transferrin saturation, ferritin levels before treatment and in the 1st and 3rd months after treatment, period of drug use, and the frequency of gastrointestinal adverse effects in the two groups were investigated.
Results: There was no difference between the two groups regarding age and sex. The mean drug dose in FeS group was 4.01±0.98 mg/kg/day and 4.12±0.06 mg/kg/day in the Fe2+-Zn group (p>0.05). The Hb, MCV, MCH, RBC, transferrin saturation, and ferritin levels in both groups in the 1st and 3rd months after treatment were found significantly higher compared with the levels before treatment. No difference was detected between the two groups for the same parameters before treatment, and in the 1st and 3rd months after treatment (p>0.05, for all). The period of drug use in Fe2+-Zn group (median:4.5 months) was longer than in the FeS group (median:4 months) (p0.05).
Conclusion: We found that FeS and Fe2+-Zn preparations had similar effects on hematologic parameters and iron status in IDA; however, the treatment period in patients who received Fe2+-Zn was longer.

Keywords: Iron deficiency anemia; divalent iron; zinco

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doi: 10.5455/annalsmedres.2020.04.291   

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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