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  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil

Editor-in-Chief

Annals of Medical Research

 

Antimicrobial activity of sapindus mukorossi and saponaria officinalis extracts on streptococcus mutans and enterococcus faecalis (p.516-9)

Antimicrobial activity of sapindus mukorossi and saponaria officinalis extracts on streptococcus mutans and enterococcus faecalis (p.516-9)

Meltem Mert Eren1, Benin Dikmen2, Cansu Vatansever3, Huseyin Servi4, Hulki Caner Yegin5, Gunce Ozan6
1Department of Restorative Dentistry, Faculty of Dentistry, Altinbas University, Istanbul, Turkey
2Department of Restorative Dentistry, Faculty of Dentistry, Medipol University, Istanbul, Turkey
3Department of Pharmaceutical Microbiology, Faculty of Pharmacology, Altinbas University, Istanbul, Turkey
4Department of Pharmaceutical Botanic, Faculty of Pharmacology, Altinbas University, Istanbul, Turkey
5Department of Department of Endodontics, Faculty of Dentistry, Altinbas University, Istanbul, Turkey
6Department of Restorative Dentistry, Faculty of Dentistry, Istanbul University, Istanbul, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: Studies on the antimicrobial effectiveness of saponins against oral pathogens are conflicting. Therefore, this study aimed to evaluate the antimicrobial activity of saponins from three different extracts of Sapindus mukorossi and Saponaria officinalis plants against Streptococcus mutans and Enterococcus faecalis.
Materials and Methods: The fruit of Sapindus mukorossi and the root of Saponaria officinalis materials were sliced into small pieces and macerated with hexane, ethyl acetate (EtOAc) and methanol (MeOH), in this order. The antimicrobial activity of the extracts against Streptococcus mutans and Enterococcus faecalis was determined by the broth microdilution method based on the minimum inhibitory concentrations (MIC) of each extract.
Results: Except for the hexane extract of Saponaria Officinalis, all extracts of both plants had an inhibitory activity against the tested microorganisms. Higher MIC values were obtained against Enterococcus faecalis than Streptococcus Mutans. The lowest MIC values for both Sapindus mukorossi and Saponaria officinalis were against Streptococcus mutans (4 mg/ml).
Conclusion: Saponins extracted from Sapindus mukorossi and Saponaria officinalis have a potential antibacterial activity against oral pathogens. They may be used as an ingredient in dental agents.

Keywords: Antimicrobial activity; Enterococcus faecalis; minimum inhibitory concentration; saponin; Streptococcus mutans

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doi: 10.5455/annalsmedres.2020.05.487   

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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