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  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil

Editor-in-Chief

Annals of Medical Research

 

The correlation between the increase rate of serum creatinine levels and long-term adverse clinical outcomes in patients with non st-segment elevation myocardial infarction (p.520-6)

The correlation between the increase rate of serum creatinine levels and long-term adverse clinical outcomes in patients with non st-segment elevation myocardial infarction (p.520-6)

Sukru Arslan, Sait Mesut Dogan
Department of Cardiology, Istanbul University, Cerrahpasa Cardiology Institute, Istanbul, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: We purposed to evaluate the correlation between the rate of increase in SCrea levels and major adverse cardiac and cerebrovascular events(MACCE) in non ST-segment elevation myocardial infarction(NSTEMI) patients who was made coronary angiography(CAG) in this study. According to studies on especially stable coronary artery disease (SCAD); contrast-induced acute kidney injury CI-AKI) is described as an rising in serum creatinine (SCrea) levels more than 0.5 mg / dl or more than 25% within 48-72 hours after the contrast agent implementation. However, data on the increase rates of SCrea levels in patients with acute coronary syndrome (ACS) are insufficient..
Materials and Methods: 884 NSTEMI patients were admitted to our study. We classified the patients into 3 groups according to the increase rates in SCrea values; first group(∆SCrea 10%), second group(10%≤ ∆SCrea 25%) and third group(∆SCrea ≥25%). Results: MACCE were defined as all-cause mortality, myocardial infarction (MI) and cerebrovascular accident (CVA) at one year follow-up. MACCE occurred in 123(13.9%) of the 884 patients. Patients in group three had a meaningfully higher rate of MACCE than in the other groups (P 0.001). This difference was primarily sourced from all-causes mortality; the all-causes mortality ratio was 3-4 times higher than the other groups. There was no meaningful difference in MACCE among first and second groups.
Conclusion: Using an increase rate of ≥25% creatinine as the definition for CI-AKI is more reliable for primary end points in patients with NSTEMI than the increase rate of creatine in lower levels.

Keywords: Contrast induced nephropathy; serum creatinine increase ratio; acute coronary syndrome; adverse clinical outcomes  

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doi: 10.5455/annalsmedres.2020.02.142   

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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