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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is published monthly.

Editor-in-Chief

 

Assessment of pulmonary functions with spirometry method in hepatic impairment patients (p.106-12)

Assessment of pulmonary functions with spirometry method in hepatic impairment patients (p.106-12)

Sadettin Demirel1, Necmiye Funda Coskun2, Selim Giray Nak3, Fadil Ozyener1
1Department of Physiology, Faculty of Medicine, Bursa Uludag University, Bursa, Turkey
2Department of Chest Diseases and Tuberculosis, Faculty of Medicine, Bursa Uludag University, Bursa, Turkey
3Department of Gastroenterology, Faculty of Medicine, Bursa Uludağ University, Bursa, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: In this study, it has been aimed to investigate whether there is a relationship between pulmonary functions measured by spirometry and hepatic impairment tables. This may contribute to a better understanding of the mechanisms of liver pathophysiology which hasn’t been fully understood.
Materials and Methods: This study is a randomized controlled prospective trial. 39-63 years of age, 19 male and 9 female, a total of 28 patients diagnosed with liver failure, with 15 male and 17 female, a total of 32 healthy volunteers with similar social characteristics were studied. All of the participants’ pulmonary parameters (FEV1, FVC, FEV1/FVC, PEF, FEF25-75%, FEF25%, FEF50%, FEF75%, PIF, VC, MVV) were performed by pulmonary function tests (PFT). Groups’ data have been analyzed statistically. The significance level was considered as p0.05.
Results: In hepatic impairment patients, there was no significant difference in terms of the expected percentage values of PFT parameters that indicate obstruction. Weak restriction in 8 cases, moderate restriction in 9 cases and severe restriction in 4 cases were diagnosed. PFT parameters of patients with mid-level and refractory ascites were found to be significantly lower compared with those without ascites (FEV1: p=0.009; FVC: p=0.010; VC: p=0.008). There was no remarkable correlation between AST, ALT, ALP, GGT levels and PFT parameters of patients as with ascites status.
Conclusion: Ascites that can frequently coexist with chronic liver disease cases, may cause restrictive type pulmonary dysfunctions in PFT by creating mechanical pressure. But also, there is no correlation between the ascites status or PFT diagnoses and liver function tests.

Keywords: Ascites; hepatic impairment; pulmonary function tests; spirometry

 

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doi:10.5455/annalsmedres.2020.09.907

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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