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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is published monthly.

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The role of right precordial intrinsicoid deflection time in determining the conversion of Type 2 Brugada ECG pattern to Type 1 Brugada ECG pattern on 12-lead electrocardiogram with ajmaline test (p.144-8)

The role of right precordial intrinsicoid deflection time in determining the conversion of Type 2 Brugada ECG pattern to Type 1 Brugada ECG pattern on 12-lead electrocardiogram with ajmaline test (p.144-8)

Orcun Ciftci1, Casit Olgun Celik1, Volkan Camkiran2, Ilyas Atar3, Bulent Ozin1
1Department of Cardiology, Faculty of Medicine, Baskent University, Ankara, Turkey
2Clinic of Cardiology, Memorial Hospital Bahcelievler Hospital, Istanbul, Turkey
3Clinic of Cardiology, Guven Hospital, Ankara, Turkey
Copyright@Author(s) - Available online at www.annalsmedres.org
Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

Aim: Brugada syndrome is a genetic disorder associated with fatal ventricular arrhythmias. Type 1 (cove-type) ECG pattern is diagnostic for Brugada syndrome while Type 2 (saddle-type) ECG pattern requires ajmaline test to convert it to Type 1 ECG pattern to make the diagnosis. However, this test may cause ventricular arrhythmias and death. Intrinsicoid deflection time (IDT) is an ECG parameter reflecting intraventricular conduction delay, which is one of the pathophysiological mechanisms for Brugada syndrome. We examined IDT for conversion of type 2 Brugada pattern to type 1 Brugada pattern in ajmaline test.
Materials and Methods: This retrospective study involved patients with Type 2 ECG pattern that was converted to Type 1 ECG pattern with ajmaline test (Group 1) and an age- and sex-matched control group with a normal ECG (Group 2). IDT was digitally measured in the lead V2, from the onset of the QRS complex to the peak of the R wave and compared between the study groups. A ROC curve was drawn to test the predictive ability of IDT for conversion to Type 1 ECG pattern.
Results: There were 28 subjects (21 men, 7 women) in Group 1 and 28 subjects (21 men, 7 women) in Group 2. Group 1 had a significantly greater IDT than Group 2 (28 (17.1-78.0) msec vs 21 (16.0-36.9) msec; p0.05). In ROC analysis, IDT significantly predicted conversion to Type 1 ECG pattern, and a cut-off value of 25 msec for IDT had a sensitivity of 55.6% and a specificity of 81.5% for predicting conversion to Type 1 ECG pattern.
Conclusion: IDT was significantly longer in patients with Type 2 ECG pattern converted to Type 1 ECG pattern by ajmaline compared with the control subjects. IDT has a good specificity and a modest sensitivity for prediction of conversion to Type 1 ECG pattern.

Keywords: Brugada syndrome; ajmaline test; intrinsicoid deflection time

 

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doi:10.5455/annalsmedres.2020.04.359

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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