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Formerly Journal of Turgut Ozal Medical Center

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear Annals of Medical Research Readers

As of the end of March 2021, I have started to work as Chief Editor at Annals of Medical Research. Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 28 years.  Our Journal, which is online as an open access journal with monthly free access, is being scanned in many national and international indexes (ULAKBIM TR Dizin, Turkish Medline, EBSCO, Google Scholar, etc.). I would like to thank the Editors before me who contributed to this level. Our primary goal is to ensure the maintenance of this good state of the journal and to ensure that it is scanned in prestigious international indexes (Pubmed Central, SCI-Expended, etc.). In order to achieve these goals, it depends on the original research articles that can be cited and the articles published in our Journal to be cited sufficiently in other international journals. The contributions of our readers, reviewers and authors in achieving this goal are of great importance.

I hope to announce the news that we have reached our goals as soon as possible.

MD. Prof. Nevzat Erdil

Editor-in-Chief

Annals of Medical Research

 

Evaluation of mean platelet volume, neutrophil/lymphocyte ratio and platelet / lymphocyte ratio relationship with disease severity and metabolic syndrome in patients with psoriasis vulgaris (p.2503-9)

Evaluation of mean platelet volume, neutrophil/lymphocyte ratio and platelet / lymphocyte ratio relationship with disease severity and metabolic syndrome in patients with psoriasis vulgaris (p.2503-9)

Hilal Semra Hancer1, Emine Tugba Alatas2
1Clinic of Dermatology, Denizli State Hospital, Denizli, Turkey
2Department of Dermatology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: Psoriasis is one of the diseases caused by chronic inflammation. It is associated with a number of comorbidities (metabolic syndrome, cardiovascular disease, obesity, non-alcholic fatty liver...). Recently, mean platelet volume (MPV), neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) were found to be related to systemic inflammation. At the end of this study, the risk of metabolic syndrome in psoriasis will be evaluated and the effect of MPV, NLR, PLR levels will be determined on predicting metabolic comorbidities in psoriasis patients.
Material and Methods: This research was planned prospectively. The study consisted of 40 patients with psoriasis vulgaris and 40 healty control group which was similar in age and gender . Patients' informations were recorded and blood pressure, height, weight values were measured. Hemogram parameters, biochemistry values were determined.
Results: The count of neutrophiles was higher in the psoriasis; but disease severity and neutrophil count were not related each other. According to our study, MPV values, high density lipoprotein (HDL), fasting blood glucose and body mass index (BMI) were meaningful findings in estimating the development of metabolic syndrome.
Conclusion: The use of neutrophil activation markers in addition to neutrophil count in patients with psoriasis may be useful in determining disease severity and activation. In the follow-up of patients with psoriasis, fasting glucose, HDL, BMI value and MPV can help predicting possibility of metabolic syndrome and cardiovascular diseases that may develop in these patients.

Keywords: Metabolic syndrome; neutrophil; platelet; psoriasis

 

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doi: 10.5455/annalsmedres.2020.07.760 

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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