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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is published monthly.

Editor-in-Chief

 

A comparison of neutrophil-lymphocyte ratio and body fat percentage in hashimoto’s disease induced hypothyroid patients (p.2625-30)

A comparison of neutrophil-lymphocyte ratio and body fat percentage in hashimoto’s disease induced hypothyroid patients (p.2625-30)

Emine Korkmaz1, Dursun Cadirci2, Mehmet Ali Eren3, Ataman Gonel4
1Halfeti Public Hospital, Sanliurfa, Turkey
2Harran University, Medical Faculty, Department of Family Medicine, Sanliurfa, Turkey
3Harran University, Medical Faculty, Department of Endocrinology, Sanliurfa, Turkey
4Harran University, Medical Faculty, Department of Biochemistry, Sanliurfa, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: Inflammatory mechanisms are activated when the body mass index is increased and in cases of Hashimoto’s Thyroiditis (HT). The neutrophil-lymphocyte ratio (NLR), which is used as a new and easily accessible inflammatory marker, may be related to the body mass index. The objective of this study is to compare the NLR and body fat percentage in patients with Hashimoto’s disease induced hypothyroidism.
Material and Methods: The study consisted of 29 patients diagnosed with HT induced hypothyroidism based on the clinical and laboratory findings. The control group consists of 29 healthy individuals who do not suffer from any disease known to increase TSH level. Body analysis is performed for all cases that are included in the study, and the height, weight, body fat percentage, lean body mass, visceral adiposity, basal metabolic rate, and body fluid percentages are calculated, and complete blood count, TSH, FT3, FT4, Anti-TPO tests were performed following 3-4 cc venous blood sample collection from all cases.
Results: There were not any significant difference between the patient and control group in terms of gender, BMI, body fat percentage, lead body mass, visceral adiposity, fluid percentage, and basal metabolic rate data (p>0.05). NLR rate was 1.95±1.37 in patient group and 2.52±1.40 in control group. Significant difference was identified in NLR (p=0.025), fat percentage (p=0.002), lean mass (p=0.002) and visceral adiposity data (p=0.006) between the HT patients and control group when the male patients were removed from the groups. NLR was identified statistically significantly low in the patient group when compared to the control group (p0.012). There was no significant correlation between NLR and lean mass, TSH, BMI, visceral adiposity, fluid percentage, and age parameters in both groups.
Conclusion: NLR, like other common inflammatory markers, is an inexpensive and easily accessible marker that can be used in hospitalized patients. However, it would be more appropriate to evaluate the conditions that may have effects on the results such as patients drug use and bone marrow suppression. It can be said that more evidence is needed to use NRL as a marker for HT management.

Keywords: Hashimoto’s thyroiditis; neutrophil-lymphocyte ratio; body fat percentage

 

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doi: 10.5455/annalsmedres.2020.07.669           

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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