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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is published monthly.

Editor-in-Chief

 

Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma (p.2022-30)

Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma (p.2022-30)

Semra Gurunluoglu1, Emine Samdanci2, Ahmet Kadir Arslan3, Nusret Akpolat2, Nurhan Sahin4, Hasan Gokce2
1Department of Medical Pathology, Malatya Turgut Ozal University Training and Research Hospital, Malatya, Turkey
2Department of Medical Pathology, Faculty of Medicine, Inonu University, Malatya, Turkey
3Department of Biostatistics and Medical Informatics, Faculty of Medicine, Inonu University, Malatya, Turkey
4Department of Medical Pathology, Faculty of Medicine, Bezmialem University, Istanbul, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: Gastric carcinoma is the fourth most common carcinoma worldwide. The relationships established between the tumor morphology and the prognosis have not been very effective until recent times. Poorly Differentiated Clusters (PDCs); are structures those can be easily identified in H&E sections. A new grading system based on PDC count has been studied in colorectal carcinoma; and found to be associated with prognosis. We have aimed to investigate this concept in gastric carcinoma.
Material and Methods: Our study included 80 cases, consisting of 16 females and 64 males having gastric carcinoma with intestinal morphology. For each case; conventional grade, PDC grade and prognostic parameters to be applied in the study were determined, and statistically compared.
Results: Significant discrepancy was found between the two grading systems. PDC tumor grades were statistically related to; median metastatic lymph node counts, metastatic lymph node ratios, lymph node stages (pN) and the presence of perineural invasion.
Conclusion: In stomach carcinoma; PDC grading system was found to be related to a significant part of the expected parameters and may have a prognostic value.

Keywords: Poorly differentiated clusters; gastric carcinoma; histologic grade

  

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doi: 10.5455/annalsmedres.2020.06.578

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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