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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is published monthly.

Editor-in-Chief

 

An investigation of the use of SCUBE1 protein as an early prognostic marker in predicting prognosis after cardiopulmonary resuscitation in cardiac arrest patients (p.2118-23)

An investigation of the use of SCUBE1 protein as an early prognostic marker in predicting prognosis after cardiopulmonary resuscitation in cardiac arrest patients (p.2118-23)

Gurkan Altuntas1, Ali Aygun2, Faruk Ozsahin3, Selim Demir4, Betül Abanoz4, Ahmet Ali Top4, Senol Ardic4, Ozgur Tatli5, Ahmet Mentese6, Suleyman Turedi5
1Department of Emergency Medicine, Rize Training and Education Hospital, Rize, Turkey
2Department of Emergency Medicine, Ordu University, Faculty of Medicine, Ordu, Turkey
3Department of Emergency Medicine, Giresun İlhan Ozdemir Training and Education Hospital, Giresun, Turkey
4Department of Nutrition and Dietetics, Faculty of Health Sciences, Karadeniz Technical University, Trabzon, Turkey
5Department of Emergency Medicine, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey
6Program of Medical Laboratory Techniques, Vocational School of Health Sciences, Karadeniz Technical University, Trabzon, Turkey

Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: To evaluate the usefulness of Signal Peptide-CUB-EGF Domain-Containing Protein-1 (SCUBE1) protein as an early prognostic marker in predicting survival, resuscitation success, and good neurological outcome following cardiopulmonary resuscitation (CPR) in cardiac arrest patients.
Material and Methods: Non-traumatic cardiac arrest patients presenting to the emergency department over a six-month period were included in the study. Blood specimens were collected for SCUBE1 measurement at the start of CPR. SCUBE1 levels investigated at the start of CPR were compared, and their usefulness in predicting patients with long-term survival and exhibiting good neurological prognosis was evaluated.
Results: The study group consisted of 65 non-traumatic cardiac arrest patients. Sustained return of spontaneous circulation (ROSC) was achieved in 26 (40%) of these 65 patients, and five (7.7%) cases concluded with good neurological prognosis after three months. Comparison of the patient groups with and without sustained ROSC in terms of SCUBE1 levels investigated at the start of CPR revealed no statistically significant difference between them (p=0.462). However, comparison of the patient groups with good and poor neurological prognosis in terms of SCUBE1 levels at the start of CPR revealed that SCUBE1 levels were twice as high in the poor neurological prognosis group as in the good neurological prognosis group, although the difference was not statistically significant.
Conclusion: SCUBE1 levels measured at the start of CPR are not sufficient for predicting post-CPR survival and good neurological outcome.

Keywords: Advanced cardiac life support; cardiopulmonary resuscitation; signal peptide 

 

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doi: 10.5455/annalsmedres.2020.02.180    

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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