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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


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  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is published monthly.

Editor-in-Chief

 

Complete Blood Count parameters could predict malignancy in breast lesions (p.2134-7)

Complete Blood Count parameters could predict malignancy in breast lesions (p.2134-7)

Bahri Ozer1, Oguz Catal1, Songul  Peltek Ozer2, Fatih Keyif1, Mustafa Sit1, Nuri Kama1
1Department of General Surgery, Abant Izzet Baysal University Hospital, Bolu, Turkey
2Department of Pathology, Abant Izzet Baysal University Hospital, Bolu, Turkey

Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: Inflammatory response plays an important role in the development and progression of various cancers, including breast cancer. The aim of present study is determining Complete Blood Count parameters as possible predictors of malignancy in breast lesions.
Material and Methods: Patients with BI-RADS-4 breast disease were studied between 2010 and 2017 retrospectively. Patients with lesions detected radiologically were included in the study. According to the histopathological results, the study cohort was divided into two groups, either benign or malignant. Final blood counts of the patients before pre-biopsy were evaluated in preoperative peripheral blood measurements. When blood was taken, care was taken not to have other causes of leukocytosis in the patient. Complete Blood Count parameters were compared in these groups.
Results: A total of 331 women with BI-RADS 4 lesions enrolled to the study. Mortality and morbidity were not observed after breast biopsy in patients. Platelet (p=0.04), platelet to lymphocyte ratio (p=0.006) and red cell distribution width to platelet ratio (p=0.032) values of the patients with BI RADS 4A were found significantly different in the malignant group compared to benign BI RADS 4A group. In total BIRADS 4 lesions, the ratio of PLT and RPR was significant in malignant group (p=0.047, p=0.002) in Complete Blood Count parameters compared benign and malignant group.
Conclusion: Studies have shown that cancer affects peripheral blood cells positively or negatively. In our study, among peripheral blood cells, platelets were found to be the most affected in cancer patients. The PLT, PLR and RPR values could be valuable in predicting malignant BIRADS 4 breast lesions.

Keywords: Breast lesions; platelet; platelet to lymphocyte ratio 

 

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doi: 10.5455/annalsmedres.2020.02.150

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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