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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is It is published monthly.

Editor-in-Chief
Cuneyt Kayaalp

 

Anticoagulants in left atrial thrombus resolution (p.1908-12)

Anticoagulants in left atrial thrombus resolution (p.1908-12)

Kerem Can Yilmaz, Orcun Ciftci, Bulent Ozin, Haldun Muderrisoglu
Department of Cardiology, Faculty of Medicine, Baskent University, Ankara, Turkey

Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: Warfarin has been used for protection from peripheral embolism in patients with atrial fibrillation (AF) and it has been shown that the direct oral anticoagulants are effective in protection against stroke as much as warfarin and cause lower bleeding complications. Our aim is to compare the efficacies of different anticoagulants in resolution of left atrial appendage thrombi.
Materials and Methods: 264 patients were included in study. 39 patients had left atrial appendage thrombus; 17 patients underwent a repeat transesophageal echocardiography (TEE) after switching/administering an anticoagulant treatment regimen.
Results: Thrombus was detected in 3 patients using apixaban, who were switched to dabigatran. Those patients were found to have thrombus resolution by the repeat TEE procedures. Of 5 patients using warfarin, 3 were switched to dabigatran, in one of whom thrombus resolution was not achieved. One patient continued warfarin with a target INR of 2.5-3.5 and a repeat TEE showed complete thrombus resolution. The remainder patient using warfarin was swithed to rivaroxaban, with complete thrombus resolution having been achieved. Two patients using edoxaban had their thrombi resolved by dabigatran. Seven patients were not receiving any anticoagulant regimen. Among these, warfarin was administered to 4 patients and apixaban to 2; repeat TEEs showed no thrombus. The remainder patient was administered low molecular weight heparin, and repeat TEE showed persistence of LAA thrombus.
Conclusion: Irrespective of patients being anticoagulated, TEE should be planned before interventional procedures and cardioversion. If thrombus develops in a patient receiving anticoagulant treatment, switching to a different anticoagulant would be a logical option.

Keywords: Atrial fibrillation; echocardiography; transesophagealfactor; Xa inhibitors; thrombosis 

 

 

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doi: 10.5455/annalsmedres.2020.03.284        

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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