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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is It is published monthly.

Editor-in-Chief
Cuneyt Kayaalp

 

Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia? (p.1918-23)

Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia? (p.1918-23)

Ilkay Er1, Ceren Cetin2, Canan Baydemir3
1Department of Neonatology, Health Sciences University, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey
2Department of Pediatric Infection Disease, Health Sciences University, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey
3Department of Bioistatistics and Medical Informatics, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey

Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: Congenital pneumonia (CP) is serious respiratory infection of the neonates. Recently introduced hematological parameter, immature reticulocyte fraction (IRF), has been investigated to gather clinical information about the prognosis of anemia as well as to measure the level of inflammatory activity in adult patients. In this study of late-preterm infants diagnosed with CP, we compared IRF with common sepsis biomarkers and evaluated its role as inflammatory biomarker in neonates.
Material and Methods: Late-preterms were categorized based on infectious vs. non-infectious etiology of the respiratory distress. Blood samples were taken at 48-72 hours after birth. IRF was measured with Sysmex XN-3000. Biomarkers such as complete blood count parameters, C-reactive protein (CRP), and procalcitonin (PCT) were used for the comparison.
Results: Total of 25 late-preterms, 14 in CP-group and 11 in transient tachypnea of the newborn (TTN) group were included study. The groups were comparable in terms of gestational age, birth weight and cesarean section rate. The proportion of prolonged membrane rupture was significantly higher in CP-group. No significant differences were found between hemoglobin, hematocrit and reticulocyte in both groups (p>0.05). The value of IRF was higher in CP-group compared to in TTN-group, although it was not statistically significant (37.8±7.2% vs. 31.6±9.4%, respectively) (p=0.08). PCT was significantly higher in CP-group (p=0.017). No differences were found in other biomarkers between the groups (p>0.05).
Conclusion: Our results suggest that PCT can be diagnostic marker in CP, but further studies are needed to confirm role of IRF in neonatal inflammation.
Conclusion: Among patients presenting to the ED with STEMI, a high lactate level is associated with mortality. Also, the difference between lactate values of the patients after PTCA is associated with the risk of mortality. Therefore, we consider that first lactate levels in ED and last lactate levels after PTCA in patients with STEMI can provide physicians with an insight into the possibility of mortality.

 

Keywords: Biomarker; immature reticulocyte fraction; neonate

 

 

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doi: 10.5455/annalsmedres.2020.02.161        

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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