2Department of Forensic Medicine, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey
3Department of Neurosurgery, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey
4Department of Neurosurgery, Faculty of Medicine, Binali Yidirim University, Erzincan, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.
Aim: The present study aims to investigate the effects of seizure or epilepsy formation on mortality and morbidity in epileptic patients after craniectomy.
Material and Methods: The patients were divided into the following groups: Group 1, those who had no seizures, but were routinely treated with 3x100 mg of epanutin daily (n=6), Group 2, those who had at least one or multiple seizures and were initiated a second antiepileptic drug in addition to 3x100 mg of epanutin daily (n=13), and Group 3, those who had multiple seizures and who were sedated or narcotized in addition to being treated with 3x100 mg of epanutin daily (n=7). All patients underwent decompressive craniectomy within a maximum period of 48 hours and their characteristics such as age, gender, localization of infarct, hemiplegia, monoplegia, operation time, Glasgow coma and outcome scales were recorded.
Results: According to the Glasgow Outcome Scale, 1 patient in Group 1, 8 patients in Group 2 and 6 patients in Group 3 died and there was a significant increase in patient losses in Group 2 and Group 3 compared to Group 1 (p0.05). 10 patients continued to live their lives with the support of home-care services and 2 patients with other forms of help.
Conclusion: It was seen that there is a high incidence of seizure and epilepsy in MMCA infarcts after decompressive craniectomy and this significantly increased mortality or dysfunctional recovery if epilepsy could not be brought under control.
Keywords: Decompressive craniectomy; epilepsy; glasgow coma scale; MMCA infarction, mortality