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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is It is published monthly.

Editor-in-Chief
Cuneyt Kayaalp

 

Decreased serum periostin level is associated with carpal tunnel syndrome (p.1584-9)

Decreased serum periostin level is associated with carpal tunnel syndrome (p.1584-9)

Seda Sabah Ozcan1, Hikmet Sacmaci2, Murat Cakir  
1Yozgat Bozok University, Faculty of Medicine, Department of Medical Biology, Yozgat, Turkey
2Yozgat Bozok University, Faculty of Medicine, Department of Neurology, Yozgat, Turkey
3Yozgat Bozok University, Faculty of Medicine, Department of Physiology, Yozgat, Turkey

Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: Noninflammatory subsynovial connective tissue (SSCT) fibrosis with nerve compression is an obvious feature of carpal tunnel syndrome (CTS). We investigated serum levels of periostin, which is known to have an effect on fibrosis, in patients with CTS.
Material and Methods: A total of 39 healthy individuals and 32 patients who were newly diagnosed with CTS were included in this prospective clinical study. Duration of symptoms, severity, unilateral or bilateral side of CTS diagnosis of patients were recorded. Serum samples were received for the measurement of periostin levels from all participants and were analyzed using commercial enzyme-linked immunosorbent assay (ELISA) kits.
Results: Serum periostin levels were significantly lower in CTS patients than controls (p=0.030). Additionally, there was no correlation between serum periostin levels and CTS disease regarding the duration of symptoms and electrophysiological severity of symptoms (p > 0.05).
Conclusion: In the current study, it was evaluated that there is a significant relation between CTS and serum periostin levels. Periostin may have roles in the pathogenesis of the CTS. This is the first study to determine serum periostin levels in CTS patients.

Keywords: Carpal tunnel syndrome; ELISA; fibrosis; periostin; serum 

 

 

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doi: 10.5455/annalsmedres.2020.05.485     

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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