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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

    In publication or citation search, the name similarities of the authors, typographical errors and institutional changes can cause confusion. To prevent this, researchers need to obtain a descriptive ID. ORCID (Open Researcher and Contributor ID) is a researcher-specific international URI with a 16-digit number. You can register for free for individual ORCID at http://orcid.org. Please indicate the ORCID number of all authors when submitting your article.

  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is It is published monthly.

Editor-in-Chief
Cuneyt Kayaalp

 

Is it important to see the coexistent seminal vesicle invasion and extracapsular extension at the radical prostatectomy specimen reports? (p.1621-5)

Is it important to see the coexistent seminal vesicle invasion and extracapsular extension at the radical prostatectomy specimen reports? (p.1621-5)

Guven Erbay1, Cuneyt Ozden2, Mehmet Murat Baykam3, Cevdet Serkan Gokkaya2, Suleyman Tagci2, Binhan Kaan Aktas2, Suleyman Bulut2, Ali Memis2
1Clinic of Urology, Karaman State Hospital, Karaman, Turkey
2Clinic of Urology, Ankara City Hospital, Ankara, Turkey
3Clinic of Urology, Faculty of Medicine, Corum Hitit University, Corum, Turkey

Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: To evaluate the effect of coexistent extracapsular extension and seminal vesicle invasion on biochemical reccurence free survival rates in patients who had undergone open radical retropubic prostatectomy.
Material and Methods: The data of 307 patients with clinically localized prostate cancer who had undergone radical retropubic prostatectomy between January 2000 and May 2019 were evaluated retrospectively. According to extension of tumor on surgical specimens, patients were classified into five groups as; organ-confined disease, extracapsular extension, isolated seminal vesicle invasion, extracapsular extension in addition to seminal vesicle invasion and lymph node involvement. Patient groups were analyzed categorically with regard to biochemical reccurence free survival rates by using Kaplan Meier analysis, log-rank and chi-square tests. The effect of pathological features of surgical specimens on biochemical reccurence was evaluated by using univariate and multivariate Cox regression analysis.
Results: There were statistically significant differences on biochemical reccurence free survival rates among the five groups, and pathological stage and biochemical reccurence rates increased correspondingly. Multivariate Cox regression analysis showed that coexistent extracapsular extension and seminal vesicle invasion, and lymph node involvement are the two significant factors that negatively effect the biochemical reccurence free survival rate.
Conclusion: Coexistence of extracapsular extension and seminal vesicle invasion is a worse prognostic factor compared to their isolated forms.

Keywords: Biochemical reccurence; extracapsular extension; prostate cancer; radical retropubic prostatectomy; seminal vesicle invasion 

 

 

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doi: 10.5455/annalsmedres.2019.04.314   

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Turkey


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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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