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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is It is published monthly.

Editor-in-Chief
Cuneyt Kayaalp

 

Routine hematological parameters do not reflect disease severity and cardiovascular risk in obstructive sleep apnea syndrome (p.1088-94)

Routine hematological parameters do not reflect disease severity and cardiovascular risk in obstructive sleep apnea syndrome (p.1088-94)

Asli Akyol Gurses1, Kadri Murat Gurses2, Utku Ogan Akyildiz3
1Gazi University, Faculty of Medicine, Department of Neurology, Division of Neurophysiology, Ankara, Turkey
2Adnan Menderes University, Faculty of Medicine, Department of Basic Health Sciences, Aydin, Turkey
3Adnan Menderes University, Faculty of Medicine, Department of Neurology, Aydin, Turkey
Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: Obstructive sleep apnea syndrome (OSAS) is characterized by transient obstruction of the upper airway and intermittent hypoxia during sleep and known to co-exist with a background low-grade systemic inflammation. In this study, we aimed to evaluate the routine hematological parameters which have recently been suggested as alternatives to specific inflammatory biomarkers and their association with disease severity and concurrent cardiovascular risk factors in OSAS.
Material and Methods: 210 patients, who were examined for sleep disordered breathing complaints and diagnosed OSAS after overnight polysomnography, were included in the study. Patients who suffer from at least one of the following disorders; diabetes mellitus, hypertension and hyperlipidemia were classified as “patients with cardiovascular risk”. Results of routine hemogram studies and polysomnographic analyses were recorded.
Results: 71% of the patients were male and 29% were female. 12% of the patients had mild, whereas 29% had moderate and 59% had severe obstructive sleep apnea syndrome. Platelet counts, mean platelet volume, platelet distribution width, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio revealed no difference among three groups of disease severity. Comparison of patients with and without cardiovascular risk either showed no difference in terms of the aforementioned parameters.
Conclusion: Our findings indicate that routine hematological parameters such as mean platelet volume, platelet distribution width, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio are not appropriate indices for predicting disease severity and cardiovascular risk in OSAS patients. As severe disease corresponds to a worse inflammatory state, these markers might not be appropriate for predicting systemic inflammation either.

Keywords: Blood count; cardiovascular risk; hematological parameters; obstructive sleep apnea syndrome

 

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doi: 10.5455/annalsmedres.2019.12.876      

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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