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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research

    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research

    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research

    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is published monthly.



Can neutrophil-lymphocyte ratio be a predictor of late-onset sepsis in preterm infants? (p.23-8)

Can neutrophil-lymphocyte ratio be a predictor of late-onset sepsis in preterm infants? (p.23-8)

Ipek Guney Varal, Pelin Dogan
University of Health Sciences, Bursa Yuksek Ihtisas Training Hospital, Department of Pediatrics, Division of Neonatology, Bursa, Turkey

Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.


Aim: Late-onset sepsis (LOS) persists to be a crucial reason of morbidity and mortality in preterm infants. Studying the effect of neutrophil-lymphocyte ratio (NLR) value in predicting the LOS episode and relation with the type of the growing microorganism were the aim of this study.
Material and Methods: Preterm infants were classified as two groups in accordance with having culture proven LOS during the stay in neonatal intensive care unit. Premature infants with culture proven LOS was defined as study group and infants with no-LOS as control group. Study group is consisting of two subgroups in terms of the growing microorganism type. NLR values were compared within and between the groups.
Results: Overall, final analysis were applied to 116 infants. NLR values were raised in the study group during LOS episode (p0.001). NLR value of the Gram-positive sepsis group (Subgroup 1) was significantly higher in comparison to Gram-negative sepsis group (Subgroup 2) (median: 2.4 and 1.8, respectively, p = 0.02). ROC analysis showed that area under the curve (AUC) of NLR was 0.723 (p0.001) and cut-off point optimized for sensitivity of 68% and a specificity of 82% was stated as NLR ≥1.57 for conforming LOS.
Conclusions: These findings demonstrated that in preterm infants, NLR values rise for the duration of a LOS episode. We believe that NLR value may be a helpful for the prediction of LOS in preterm infants.

Keywords: Late-onset sepsis; neutrophil/lymphocyte ratio; preterm



doi: 10.5455/annalsmedres.2020.01.023


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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.


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