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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research



    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research


    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research


    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is published monthly.

Editor-in-Chief

 

The predictive value of laboratory factors in evaluating the necessity of surgical treatment in Crohn’s disease (p.105-9)

The predictive value of laboratory factors in evaluating the necessity of surgical treatment in Crohn’s disease (p.105-9)

Emine Ozlem Gur1, Elif Saritas Yuksel2, Selda Haciyanli1, Cem Cekic2, Osman Nuri Dilek1, Mehmet Haciyanli1
1Katip Celebi University Ataturk Training and Research Hospital, Department of General Surgery, Izmir, Turkey
2Katip Celebi University Ataturk Training and Research Hospital, Department of Gastroenterology, Izmir, Turkey

Copyright © 2020 by authors and Annals of Medical Research Publishing Inc.

Abstract

Aim: The primary treatment of Crohn’s disease (CD) is medical but approximately 70% of all patients with CD undergo surgical intervention throughout their lives. We aimed to determine which parameters can guide decision making before surgical treatment and to determine the effectiveness of the Glasgow prognostic index (GPI) and prognostic nutritional index (PNI) in predicting the necessity of surgery.
Material and Methods: Patients who underwent surgery or medical treatment for CD were matched for age and sex. Group 1: operated patients; Group 2: received medical treatment. Hemogram and biochemistry test results were recorded. Platelet to neutrophil ratio (PNR), Neutrophil to lymphocyte ratio (NLR), and Lymphocyte to monocyte ratio (LMR) were calculated. Patients who had both a serum elevation of CRP (>1.0 mg/dL) and hypoalbuminemia (3.5 g/dL) were allocated a GPI of 2. Patients with only one of the abnormal values were allocated a GPI of 1, and patients who had neither were allocated a GPI 0. Parameters compared statistically between groups. The value p0.05 was accepted significant.
Results: Of the 104 patients 51 were in Group 1 and 53 were in Group 2. The number of patients with a GPI value of 3 was significantly higher in Group 1 than in Group 2 (p 0.05), as were NLR, protein, albumin, neutrophil, platelet, and CRP levels (p 0.05). The multivariate analysis revealed that albumin and GPI values were independent variables in predicting the likelihood of receiving an operation in CD.
Conclusion: In conclusion, evaluating the necessity of surgical treatment during follow-up for CD, neutrophil, NLR, CRP, albumin, platelet, PNI, and GPI, can be used. If the GPI value is 2 in a patient with CD under follow-up whose albumin levels are low, then surgical treatment should be considered.

Keywords: Crohn’s disease; blood test; surgery;medical treatment

 

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doi: 10.5455/annalsmedres.2019.11.761

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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.

 

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