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Formerly Journal of Turgut Ozal Medical Center - ISSN 1300-1744

  • Annals of Medical Research

    Annals of Medical Research International Monthly Published Medical Journal

  • Annals of Medical Research

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  • Annals of Medical Research

    Annals of Medical Research indexed in TÜBİTAK/ULAKBİM Tıp Veri Tabanı

  • Annals of Medical Research

    Annals of Medical Research indexed in

  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research
  • Annals of Medical Research

Dear readers,

Our journal is the official publication of Inonu University Medical Faculty and published uninterruptedly for 25 years. It was first published as the name of Inonu University Medical Journal and later as Journal of Turgut Ozal Medical Center. During its publication period, the journal accepted Turkish or English articles for publication.

Abstracting in an international index is just a paramount objective in the 25th year of the journal. Because of this goal, it was necessary to make a decision both in terms of journal name and publication language. It was important in this respect that the name of a general medical journal should be related to medicine again and it should be in English. For these reasons, the name of the journal was switched to Annals of Medical Research and its publication language is changed to in English. The logo of the journal was chosen as an apricot, which is the symbol of our city Malatya, the world capital of apricot. I hope the journal succeeds with its new name. Annals of Medical Research is It is published monthly.

Cuneyt Kayaalp


Evaluation of the effects of various agents on aggregatibacter actinomycetemcomitans, candida albicans, and streptococcus mutans growth (p. 2733-7)

Evaluation of the effects of various agents on aggregatibacter actinomycetemcomitans, candida albicans, and streptococcus mutans growth (p. 2733-7)

Mehmet Murat Taskan1, Isa Karaman2, Hatice Balci Yuce1, Gozde Isiker Kara1
1Tokat Gaziosmanpasa University, Faculty of Dentistry, Department of Periodontology, Tokat, Turkey
2Tokat Gaziosmanpasa University, Faculty of Engineering and Natural Science, Tokat, Turkey


Aim: Oral environment hosts many microorganisms and even symbiotic microorganisms can cause diseases under appropriate conditions and antimicrobial therapy might be required. The aim of the present study was to evaluate the effect of various antioxidants on Aggregatibacter actinomycetemcomitans, Candida albicans, and Streptococcus mutans as pathogenic microorganisms of the oral environment.
Material and Methods: In present research, the antibacterial effects of various antioxidants on oral bacteria, Aggregatibacter actinomycetemcomitans (A.actinomycetemcomitans, ATCC 33384), Streptococcus mutans (S.mutans, ATCC 35668), and fungus Candida albicans (C.albicans, ATCC 90819) were tested. The tested antioxidants were curcumin, gallic acid, and vanillic acid. The concentrations of the antioxidants were adjusted to 5% and appropriate solvents were used for the agents. The solvents were distilled water for gallic acid, ethanol for vanillic acid and dimethyl sulphoxide (DMSO) for curcumin. Antibiotics ciprofloxacin, penicillin, tetracycline, and chlorhexidine were used as positive control agents. The antibacterial effect of the antioxidants were tested with disc-diffusion method.
Results: Positive control agents provided significant antibacterial efficacy compared to the test agents and negative controls. The most significant effect was observed on ciprofloxacin against all tested microorganisms. On the other hand, penicillin provided similar effects with the chlorhexidine and tetracycline. All antioxidants tested in the present study was found ineffective against all tested microorganisms. Topical use of antioxidants did not provide efficacy.
Conclusion: Antioxidants have significant effects on preventing oxidative stress and decreasing inflammation-driven pathologies. However, the tested antioxidants did not provide an antibacterial effect against A.actinomycetemcomitans, S.mutans, and C.albicans.

Keywords: A. actinomycetemcomitans; antioxidants; C.albicans, S.mutans


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Annals of Medical Research is the scientific official journal of the Inonu University Faculty of Medicine. It is published monthly. The essential aim of the Annals of Medical Research is to publish scientifically high quality clinical and experimental research articles on fields of medicine which can contribute to the literature data. In addition, review articles, case reports, editorials, letters to the editors and manuscripts on publication ethics and medical history, which can contribute to the education and practices of physicians and health sector professionals within the scope of the journal’s target audience and which can increase the level of scientific communication between the authors and readers, are included in the scope of the journal.


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