1Samsun Women’s and Children’s Hospital, Samsun, Turkey
2Ondokuz Mayis University, Faculty of Medicine, Department of Obstetrics and Gynecology, Samsun, Turkey
3Ondokuz Mayis University, Faculty of Medicine, Department of Biochemistry, Samsun, Turkey
4Amasya University Research Hospital, Department of Obstetrics and Gynecology, Amasya, Turkey
Aim: To determine the efficiency of serum amyloid-A (SAA) in predicting preterm premature rupture of membrane (PPROM) and chorioamnionitis in risky cases.
Study Design: The study consists of 20 women 26-37 weeks of pregnancy who had PPROM and 20 pregnant women without water breaks. Levels of SAA were determined in maternal venous and umbilical cord blood.
Results: SAA values in cord blood and venous blood of mothers with PPROM were higher than in the control group (p0,05). SAA values in the patients with clinical chorioamnionitis (n=9) were significantly higher (p0,05) than both PPROM patients without chorioamnionitis (n=11) and the control group (n=20).
Conclusion: In women at risk for PPROM in whom diagnosis cannot be established, blood SSA levels can be used as a marker. Increased SAA values in pregnant women with PPROM who were conservatively treated were considered a marker for chorioamnionitis.
Keywords: Premature rupture of membrane; chorioamnionitis; serum Amiloid A