Evaluation of oxidative stress in angiography workers

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Ali Mahir Gunduz
Canan Demir


Aim: In this study, we wanted to investigate the oxidative stress level and some antioxidant parameters in angiography workers exposed to high dose x-ray. Material and Methods: The study included 47 angiography workers and 50 healthy control group. Some antioxidant parameters (superoxide dismutase, catalase, and reduced glutathione) and levels of malondialdehyde, which is a marker of oxidative stress, were measured in the blood samples of all participants.Results: There was a significant increase in oxidative stress marker MDA levels and a significant decrease in antioxidant enzyme (superoxide dismutase, catalase and reduced glutathione) levels in all individuals of the study group compared to the control group (p0.001 for all). Conclusion: Our results indicated that oxidative stress level increased and some antioxidant enzyme levels (superoxide dismutase, catalase and decreased glutathione) decreased in angiography workers exposed to long-term high-dose ionized radiation. We have linked this to the oxidant-antioxidant balance disorder caused by increased free radicals due to ionizing radiation, as noted in the literature.


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Mahir Gunduz, A., & Demir, C. (2021). Evaluation of oxidative stress in angiography workers . Annals of Medical Research, 27(9), 2382–2385. Retrieved from https://annalsmedres.org/index.php/aomr/article/view/939
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