Effects of alliin on renal ischemia reperfusion induced lung injury

Authors

  • Mustafa Can Guler
  • Ersen Eraslan

Keywords:

Alliin, kidney ischemia reperfusion, lung, oxidative stress

Abstract

Aim: Renal ischemia reperfusion (I/R) injury is a problematic process which leads to renal dysfunction and may be mortal for the patients in intensive care units. Increased oxidant molecules and decreased antioxidant molecules were detected in renal I/R-induced lung injury. In the present study, it was aimed to investigate the effect of Alliin on oxidative stress in renal I/R-induced lung injury. Material and Methods: A total of 32 Wistar Albino male rats were randomly divided into 4 groups (n = 8): Sham, I/R, I/R+Alliin 100 mg/kg and I/R+Alliin 200 mg/kg group. The effects of Alliin on oxidant and antioxidant molecules were evaluated via biochemical methods.Results: Alliin treatment increased antioxidant parameters and decreased oxidant parameters.Conclusion: Alliin has been shown to reduce oxidative stress and renal I/R-induced lung injury.

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Published

2021-05-25

How to Cite

Can Guler, M., & Eraslan, E. (2021). Effects of alliin on renal ischemia reperfusion induced lung injury . Annals of Medical Research, 27(4), 1003–1007. Retrieved from https://annalsmedres.org/index.php/aomr/article/view/743

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Section

Original Articles

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