Differences in the clinical course, laboratory and radiological findings of COVID-19 infection between male, female and pregnant patients in demographically homogeneous groups

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Hilal Gulsum Turan Ozsoy
Serhat Unal
Isa Kilic
Behiye Oral

Abstract

Aim: This study examines for any differences in the clinical course, laboratory and radiological findings of COVID-19 infection between male, female and pregnant patients in similar age groups.


Materials and Methods: This  retrospective study involved a review of the data of patients treated between March 2020 and May 2021, included a total of 528 cases (193 pregnant females, 170 non-pregnant females and 165 males) aged 18–40 years with RT-PCR-confirmed COVID-19.


Results: A comparison of the three demographically homogeneous groups revealed more common symptomatic infection at admission in the male patient group than in the other two patient groups (p<0.001), as well as a longer hospital stay (p<0.001) and higher incidences of moderate and severe pneumonia (p<0.001) based on radiological findings. In contrast, no significant difference was noted in the intensive care unit admission and mortality rates of the three groups.


Conclusion: The results of our study reveal that females have some degree of protection against severe presentations of COVID-19 infection when compared to men. The heterogeneity of immunocompetence and immune response can help to understand the different COVID-19 responses of males and females, and can be used as a guide for disease prognosis and gender-specific treatments.

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How to Cite
Turan Ozsoy, H. G., Unal, S., Kilic, I., & Oral, B. (2023). Differences in the clinical course, laboratory and radiological findings of COVID-19 infection between male, female and pregnant patients in demographically homogeneous groups. Annals of Medical Research, 30(1), 70–75. Retrieved from https://annalsmedres.org/index.php/aomr/article/view/4196
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Original Articles