The relationship between preoperative and postoperative neutrophil-lymphocyte and platelet-lymphocyte ratio with post-dural-puncture headache in patients undergoing cesarean section
Mehmet Sargin1, Mehmet Selcuk Uluer2, Mahmut Sami Tutar2
1Selcuk University, Faculty of Medicine Department of, Anesthesiology and Reanimation, Konya, Turkey
2Konya Training and Research Hospital, Department of, Anesthesiology and Reanimation, Konya Turkey
Aim: This study aims to evaluate whether there is a possible relationship between the preoperative and early postoperative period neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio and post-dural-puncture headache in patients undergoing cesarean section.
Material and Methods: Two hundred twenty pregnant women scheduled to undergo elective cesarean section under spinal anesthesia, were studied. Patiens demografic data and blood count parameters were noted. Blood was sampled from a peripheral vein for neutrophil/lymphocyte ratio ve platelet/lymphocyte ratio. The time points for sampling blood were as follows: Preoperative; 1 day before and postoperative; within 6-12 hours after cesarean section. The patients were questioned for possible occurrence of spinal anesthesia induced headache on the first and seventh postoperative days. Post-dural puncture headache was evaluated according to the International Classification of Headache Disorders (ICHD-II) diagnostic criteria.
Results: A total of 220 patients were enrolled in the study and 217 patients completed the investigation. Post-dural puncture headache was detected in 78 patients and the incidence was 35.9%. The measurements of laboratory parameters were statistically similar between two groups (P > 0.05).
Conclusion: Our study results showed no relationship between the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, and post-dural-puncture headache in the preoperative and also, early postoperative period in patients who undergoing cesarean section.