A retrospective study on the effects of diabetes mellitus on perioperative fibrinogen and bleeding amount in coronary artery bypass surgery patients
Ersagun Tugcugil1, Basar Erdivanli2, Ahmet Sen3, Ahmet Besir1
1Karadeniz Technical University, Anesthesiology and Intensive Care Medicine, Trabzon, Turkey
2Recep Tayyip Erdoğan University, Anesthesiology and Intensive Care Medicine, Trabzon, Turkey
3Kanuni Education and Research Hospital, Anesthesiology and Intensive Care Medicine, Trabzon, Turkey
Aim: In this study, the effects of changes in the coagulation system of diabetic patients that undergo heart surgery on postoperative bleeding amount and complications was investigated.
Material and Methods: A total of 106 patients (35 females, 71 males) were retrospectively examined in the study. Patients were divided into two groups: diabetic (Group D, n = 47) and non-diabetic (Group C, n = 59). Preoperative and postoperative hematologic values, postoperative bleeding, and transfusion amounts of all groups were recorded.
Results: Preoperative and postoperative fibrinogen and C-reactive protein (CRP) values in Group D were significantly higher compared to those in Group C (p< 0.05 and p< 0.01, respectively). Postoperative bleeding amount, erythrocyte, and fibrinogen transfusion need were found to be significantly lower in Group D compared to Group C (p = 0.04, p = 0.01, and p< 0.001, respectively).
Conclusion: Diabetic patients had decreased amount ofpostoperative bleeding, possibly due to a thrombotic tendency caused by chronic inflammation related to diabetes mellitus.